Microarray Analysis Reveals Increased Expression of Matrix Metalloproteases and Cytokines of Interleukin-20 Subfamily in the Kidneys of Neonate Rats Underwent Unilateral Ureteral Obstruction: A Potential Role of IL-24 in the Regulation of Inflammation and Tissue Remodeling

Microarray Analysis Reveals Increased Expression of Matrix Metalloproteases and Cytokines of Interleukin-20 Subfamily in the Kidneys of Neonate Rats Underwent Unilateral Ureteral Obstruction: A Potential Role of IL-24 in the Regulation of Inflammation and Tissue Remodeling

Background/Aims: Congenital obstructive nephropathy (CON) is the main cause of pediatric chronic kidney diseases leading to renal fibrosis. High morbidity and limited treatment opportunities of CON urge the better understanding of the underlying molecular mechanisms. Methods: To identify the differe...

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Bibliographic Details
Main Authors: Domonkos Pap, Erna Sziksz, Zoltán Kiss, Réka Rokonay, Apor Veres-Székely, Rita Lippai, István Márton Takács, Éva Kis, Andrea Fekete, György Reusz, Adam Vannay, Attila J. Szabó
Format: Article
Language:English
Published: Karger Publishers 2017-02-01
Series:Kidney & Blood Pressure Research
Subjects:
Newborn
Congenital obstructive nephropathy
Unilateral ureteral obstruction
CKD
Microarray
MMP-12, IL-24
Online Access:http://www.karger.com/Article/FullText/464317

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http://www.karger.com/Article/FullText/464317

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