Preparation of Reduction-Responsive Camptothecin Nanocapsules by Combining Nanoprecipitation and In Situ Polymerization for Anticancer Therapy

Preparation of Reduction-Responsive Camptothecin Nanocapsules by Combining Nanoprecipitation and In Situ Polymerization for Anticancer Therapy

Stimuli-responsive systems for controlled drug release have been extensively explored in recent years. In this work, we developed a reduction-responsive camptothecin (CPT) nanocapsule (CPT-NC) by combining nanoprecipitation and in situ polymerization using a polymerized surface ligand and a disulfid...

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Bibliographic Details
Main Authors: Xiao-Qing Song, Cheng Tao, Wei Li, Jie-Xin Wang, Yuan Le, Jian-Jun Zhang
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Pharmaceutics
Subjects:
reduction-responsive
nanocapsule
disulfide bond
in situ polymerization
anticancer therapy
Online Access:http://www.mdpi.com/1999-4923/10/4/173

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http://www.mdpi.com/1999-4923/10/4/173

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