The effects of apolipoprotein E genotype, α‐synuclein deficiency, and sex on brain synaptic and Alzheimer's disease–related pathology

Abstract Introduction Alzheimer's disease (AD) and synucleinopathies share common pathological mechanisms. Apolipoprotein E4 (apoE4), the most prevalent genetic risk factor for AD, also increases the risk for dementia in pure synucleinopathies. We presently examined the effects of α‐synuclein d...

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Bibliographic Details
Main Authors: Roni Bar, Anat Boehm‐Cagan, Ishai Luz, Yarden Kleper‐Wall, Daniel M. Michaelson
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Sex
Online Access:https://doi.org/10.1016/j.dadm.2017.08.003