Translational control of nicotine-evoked synaptic potentiation in mice and neuronal responses in human smokers by eIF2α
Adolescents are particularly vulnerable to nicotine, the principal addictive component driving tobacco smoking. In a companion study, we found that reduced activity of the translation initiation factor eIF2α underlies the hypersensitivity of adolescent mice to the effects of cocaine. Here we report...
Main Authors: | Andon N Placzek, David L Molfese, Sanjeev Khatiwada, Gonzalo Viana Di Prisco, Wei Huang, Carmela Sidrauski, Krešimir Krnjević, Christopher L Amos, Russell Ray, John A Dani, Peter Walter, Ramiro Salas, Mauro Costa-Mattioli |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-03-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/12056 |
Similar Items
-
Translational control by eIF2α phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine
by: Wei Huang, et al.
Published: (2016-03-01) -
The Effect of L-arginine in the Ventral Tegmenta Area on the Improving Effect of Nicotine on Memory
by: MS Shahin, et al.
Published: (2012-08-01) -
The Effect of L-arginine in the Ventral Tegmenta Area on the Improving Effect of Nicotine on Memory
by: Shahin M.S, et al.
Published: (2012-09-01) -
Cocaine Inhibition of Nicotinic Acetylcholine ReceptorsInfluences Dopamine Release
by: Alexandra eAcevedo-Rodriguez, et al.
Published: (2014-09-01) -
Minimal Circuit Model of Reward Prediction Error Computations and Effects of Nicotinic Modulations
by: Nicolas Deperrois, et al.
Published: (2019-01-01)