Biological Role and Clinical Implications of microRNAs in BRCA Mutation Carriers

Women with pathogenic germline mutations in BRCA1 and BRCA2 genes have an increased risk to develop breast and ovarian cancer. There is, however, a high interpersonal variability in the modality and timing of tumor onset in those subjects, thus suggesting a potential role of other individual’s genet...

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Main Authors: Chiara Tommasi, Benedetta Pellegrino, Daniela Boggiani, Angelica Sikokis, Maria Michiara, Vera Uliana, Beatrice Bortesi, Francesco Bonatti, Paola Mozzoni, Silvana Pinelli, Anna Squadrilli, Maria Vittoria Viani, Diana Cassi, Giuseppe Maglietta, Marco Meleti, Antonino Musolino
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.700853/full