The Role of AGE/RAGE Signaling in Diabetes-Mediated Vascular Calcification

AGE/RAGE signaling has been a well-studied cascade in many different disease states, particularly diabetes. Due to the complex nature of the receptor and multiple intersecting pathways, the AGE/RAGE signaling mechanism is still not well understood. The purpose of this review is to highlight key area...

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Bibliographic Details
Main Authors: Amber M. Kay, C. LaShan Simpson, James A. Stewart
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2016/6809703