Principles of RNA processing from analysis of enhanced CLIP maps for 150 RNA binding proteins

Principles of RNA processing from analysis of enhanced CLIP maps for 150 RNA binding proteins

Abstract Background A critical step in uncovering rules of RNA processing is to study the in vivo regulatory networks of RNA binding proteins (RBPs). Crosslinking and immunoprecipitation (CLIP) methods enable mapping RBP targets transcriptome-wide, but methodological differences present challenges t...

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Bibliographic Details
Main Authors: Eric L. Van Nostrand, Gabriel A. Pratt, Brian A. Yee, Emily C. Wheeler, Steven M. Blue, Jasmine Mueller, Samuel S. Park, Keri E. Garcia, Chelsea Gelboin-Burkhart, Thai B. Nguyen, Ines Rabano, Rebecca Stanton, Balaji Sundararaman, Ruth Wang, Xiang-Dong Fu, Brenton R. Graveley, Gene W. Yeo
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Genome Biology
Subjects:
eCLIP
CLIP-seq
RNA binding protein
RNA processing
Online Access:http://link.springer.com/article/10.1186/s13059-020-01982-9

Internet

http://link.springer.com/article/10.1186/s13059-020-01982-9

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