CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression

CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression

Luminal B breast cancers (BC) have a more aggressive behavior associated with a higher rate of tumor relapse and worse prognosis compared to luminal A tumors. In this study, we evaluated the involvement of specific epithelial-to-mesenchymal transition- (EMT-) and immune-related pathways in the disse...

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Bibliographic Details
Main Authors: Carlotta Raschioni, Giulia Bottai, Andrea Sagona, Valentina Errico, Alberto Testori, Wolfgang Gatzemeier, Fabio Corsi, Corrado Tinterri, Massimo Roncalli, Libero Santarpia, Luca Di Tommaso
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2018/5018671

Internet

http://dx.doi.org/10.1155/2018/5018671

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