Neuronal neprilysin overexpression is associated with attenuation of Aβ-related spatial memory deficit
Converging evidence links abnormally high brain concentrations of amyloid-β peptides (Aβ) to the pathology of Alzheimer's disease (AD). Lowering brain Aβ levels, therefore, is a therapeutic strategy for the treatment of AD. Neuronal neprilysin upregulation led to increased degradation of Aβ, re...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2006-12-01
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| Series: | Neurobiology of Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996106001999 |