MicroRNA-27b-3p Promotes Tumor Progression and Metastasis by Inhibiting Peroxisome Proliferator-Activated Receptor Gamma in Triple-Negative Breast Cancer

MicroRNA-27b-3p Promotes Tumor Progression and Metastasis by Inhibiting Peroxisome Proliferator-Activated Receptor Gamma in Triple-Negative Breast Cancer

Introduction: The role and underlying mechanisms of miR-27b-3p in triple-negative breast cancer (TNBC) remains unclear.Methods: miR-27b-3p expression level was evaluated in 99 TNBC patients with a median follow-up time of 133 months. The biological functions of miR-27b-3p by targeting PPARG were ass...

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Bibliographic Details
Main Authors: Song-Jie Shen, Yu Song, Xin-Yu Ren, Ya-Li Xu, Yi-Dong Zhou, Zhi-Yong Liang, Qiang Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
triple-negative breast cancer
microRNA-27b-3p
PPARG
prognosis
metastasis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01371/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01371/full

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