Pragmatic trials: ignoring a mediator and adjusting for confounding

Abstract Objectives In pragmatic trials, the new treatment is compared with usual care (heterogeneous control arm) that makes the comparison of the new treatment with each treatment within the control arm more difficult. The usual assumption is that we can fully capture the relations between differe...

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Bibliographic Details
Main Author: Paraskevi Pericleous
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Research Notes
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13104-019-4188-1