Perospirone, a Novel Antipsychotic Agent, Hyperpolarizes Rat Dorsal Raphe Neurons via 5-HT1A Receptor

ABSTRACT: To investigate the effect of cis-N-[4-[4-(1,2-benz-isozole-3-yl)-1-piperazinyl]butyl] cyclohexane-1,2-dicarboximide hydrochloride (perospirone), a novel antipsychotic agent with high affinities for D2/5-HT2 receptors, on the rat dorsal raphe (DR) neurons, an electrophysiological study was...

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Bibliographic Details
Main Authors: Tsuguka Shiwa, Taku Amano, Hiroaki Matsubayashi, Takahiro Seki, Masashi Sasa, Norio Sakai
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319326222