Evolutionary dynamics and structural consequences of de novo beneficial mutations and mutant lineages arising in a constant environment

Evolutionary dynamics and structural consequences of de novo beneficial mutations and mutant lineages arising in a constant environment

Abstract Background Microbial evolution experiments can be used to study the tempo and dynamics of evolutionary change in asexual populations, founded from single clones and growing into large populations with multiple clonal lineages. High-throughput sequencing can be used to catalog de novo mutati...

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Bibliographic Details
Main Authors: Margie Kinnersley, Katja Schwartz, Dong-Dong Yang, Gavin Sherlock, Frank Rosenzweig
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Biology
Subjects:
E. coli
Adaptation
Experimental evolution
Clonal interference
Parallelism
Resource limitation
Online Access:https://doi.org/10.1186/s12915-021-00954-0

Internet

https://doi.org/10.1186/s12915-021-00954-0

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