CBA: Cluster-Guided Batch Alignment for Single Cell RNA-seq

The power of single-cell RNA sequencing (scRNA-seq) in detecting cell heterogeneity or developmental process is becoming more and more evident every day. The granularity of this knowledge is further propelled when combining two batches of scRNA-seq into a single large dataset. This strategy is howev...

Full description

Bibliographic Details
Main Authors: Wenbo Yu, Ahmed Mahfouz, Marcel J. T. Reinders
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.644211/full