Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults.

Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults.

Studying ethnically diverse groups is important for furthering our understanding of biological mechanisms of disease that may vary across human populations. The ε4 allele of apolipoprotein E (APOE ε4) is a well-established risk factor for Alzheimer's disease (AD), and may confer anatomic and fu...

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Bibliographic Details
Main Authors: Jennifer S Yokoyama, Allen K L Lee, Leonel T Takada, Edgar Busovaca, Luke W Bonham, Steven Z Chao, Marian Tse, Jing He, Christopher G Schwarz, Owen T Carmichael, Brandy R Matthews, Anna Karydas, Michael W Weiner, Giovanni Coppola, Charles S DeCarli, Bruce L Miller, Howard J Rosen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4349764?pdf=render

Internet

http://europepmc.org/articles/PMC4349764?pdf=render

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