Small extrachromosomal circular DNA (eccDNA): major functions in evolution and cancer

Abstract Extrachromosomal circular DNA (eccDNA) refers to a type of circular DNA that originate from but are likely independent of chromosomes. Due to technological advancements, eccDNAs have recently emerged as multifunctional molecules with numerous characteristics. The unique topological structur...

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Bibliographic Details
Main Authors: Xiaoxuan Ling, Yali Han, Jinxue Meng, Bohuan Zhong, Jialong Chen, He Zhang, Jiheng Qin, Jing Pang, Linhua Liu
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-021-01413-8