Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease

Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease

Diabetic kidney disease (DKD) is the leading cause of end-stage renal failure, but therapeutic options for nephroprotection are limited. Oxidative stress plays a key role in the pathogenesis of DKD. Our previous studies demonstrated that tetramethylpyrazine nitrone (TBN), a novel nitrone derivative...

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Bibliographic Details
Main Authors: Mei Jing, Yun Cen, Fangfang Gao, Ting Wang, Jinxin Jiang, Qianqian Jian, Liangmiao Wu, Baojian Guo, Fangcheng Luo, Gaoxiao Zhang, Ying Wang, Lipeng Xu, Zaijun Zhang, Yewei Sun, Yuqiang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
diabetic kidney disease
nephroprotection
metabolic abnormalities
oxidative stress
mitochondrial function
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.680336/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.680336/full

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