Chitosan-alginate capsules as oral delivery system for insulin: studies in vitro and in vivo

The aim of this study was to assess chitosan:alginate capsules as gastric resistant systems for oral administration of insulin. Chitosan:alginate capsules of insulin were tested in simulated gastric and intestinal media and in vivo. The capsules released only about 20% of the insulin after 60 minute...

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Bibliographic Details
Main Authors: C. Bürger, S. Maffezzolli, P. Clasen, R.M. Lucinda-Silva, C.A. Rodrigues
Format: Article
Language:English
Published: São Paulo State University (UNESP) 2008-09-01
Series:Revista de Ciências Farmacêuticas Básica e Aplicada
Subjects:
Online Access:http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/467