Multipotent Hematopoietic Progenitors Divide Asymmetrically to Create Progenitors of the Lymphomyeloid and Erythromyeloid Lineages

Hematopoietic stem and progenitor cells (HSPCs) can self-renew and create committed progenitors, a process supposed to involve asymmetric cell divisions (ACDs). Previously, we had linked the kinetics of CD133 expression with ACDs but failed to detect asymmetric segregation of classical CD133 epitope...

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Bibliographic Details
Main Authors: André Görgens, Anna-Kristin Ludwig, Michael Möllmann, Adalbert Krawczyk, Jan Dürig, Helmut Hanenberg, Peter A. Horn, Bernd Giebel
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114003014