Prokineticin receptor 1 as a novel suppressor of preadipocyte proliferation and differentiation to control obesity.

BACKGROUND: Adipocyte renewal from preadipocytes occurs throughout the lifetime and contributes to obesity. To date, little is known about the mechanisms that control preadipocyte proliferation and differentiation. Prokineticin-2 is an angiogenic and anorexigenic hormone that activate two G protein-...

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Bibliographic Details
Main Authors: Cécilia Szatkowski, Judith Vallet, Mojdeh Dormishian, Nadia Messaddeq, Phillippe Valet, Mounia Boulberdaa, Daniel Metzger, Pierre Chambon, Canan G Nebigil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3852222?pdf=render