Evaluation of Serum/Urine Genomic and Metabolomic Profiles to Improve the Adherence to Sildenafil Therapy in Patients with Erectile Dysfunction

Evaluation of Serum/Urine Genomic and Metabolomic Profiles to Improve the Adherence to Sildenafil Therapy in Patients with Erectile Dysfunction

Type V-phosphodiesterase-inhibitors (PDE5i) are the first choice drugs in the treatment of erectile dysfunction (ED), being effective in 60–70% of patients. However, approximately 50% of patients per year discontinue the treatment with PDE5i after reporting poor drug efficacy or major adverse drug r...

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Bibliographic Details
Main Authors: Maria Santa Rocca, Alessia Vignoli, Leonardo Tenori, Marco Ghezzi, Maurizio De Rocco Ponce, Giannis Vatsellas, Dimitris Thanos, Roberto Padrini, Carlo Foresta, Luca De Toni
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
drug safety
adherence
adverse drug reactions
translational research
nuclear magnetic resonance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.602369/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.602369/full

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