Evaluation of Renal Anionic Secretion Following Living-donor and Deceased-donor Renal Transplantation: A Clinical Pharmacokinetic Study of Cefoxitin Microdosing

Evaluation of Renal Anionic Secretion Following Living-donor and Deceased-donor Renal Transplantation: A Clinical Pharmacokinetic Study of Cefoxitin Microdosing

Background. Renal transplantation is the treatment of choice for patients with end-stage renal disease. Because kidneys are the primary excretory organs for various drugs/drug metabolites, changes in renal graft function would significantly alter the clearance and exposure of renally secreted drugs....

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Main Authors: Hari V. Kalluri, PharmD, PhD, Puneet Sood, MD, Wenchen Zhao, BS, Parmjeet S. Randhawa, MD, Amit D. Tevar, MD, Sundaram Hariharan, MD, Abhinav Humar, MD, Raman Venkataramanan, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2020-06-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001001

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http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001001

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