Role of IQGAP3 in metastasis and epithelial–mesenchymal transition in human hepatocellular carcinoma

Role of IQGAP3 in metastasis and epithelial–mesenchymal transition in human hepatocellular carcinoma

Abstract Background Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide owing to its high rates of metastasis and recurrence. The oncogene IQ motif-containing GTPase activating protein 3 (IQGAP3) is ubiquitously overexpressed in several human cancers, including liver, ovary, l...

Full description

Bibliographic Details
Main Authors: Yongjie Shi, Nan Qin, Qiang Zhou, Yanqiu Chen, Sicong Huang, Bo Chen, Gang Shen, Hongyun Jia
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Journal of Translational Medicine
Subjects:
IQGAP3
Hepatocellular carcinoma
Metastasis
Epithelial–mesenchymal transition
TGF-β signaling
Online Access:http://link.springer.com/article/10.1186/s12967-017-1275-8

Internet

http://link.springer.com/article/10.1186/s12967-017-1275-8

Similar Items