Macroautophagy in Dendritic Cells Controls the Homeostasis and Stability of Regulatory T Cells

Summary: Regulatory T cells (Tregs) play a crucial role in controlling autoimmune and inflammatory responses. Recent studies have demonstrated that dendritic cells (DCs) contribute to the homeostasis of peripheral Tregs. Autophagy, a critical pathway for cellular homeostasis, is active in DCs and is...

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Bibliographic Details
Main Authors: Jennifer Niven, Natacha Madelon, Nicolas Page, Assunta Caruso, Guillaume Harlé, Sylvain Lemeille, Christian A. Seemayer, Stéphanie Hugues, Monique Gannagé
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719307570