Synthesis of [13C4]-labeled ∆9-Tetrahydrocannabinol and 11-nor-9-Carboxy-∆9-tetrahydrocannabinol as Internal Standards for Reducing Ion Suppressing/Alteration Effects in LC/MS-MS Quantification

(−)-∆9-Tetrahydrocannabinol is the principal psychoactive component of the cannabis plant and also the active ingredient in some prescribed drugs. To detect and control misuse and monitor administration in clinical settings, reference samples of the native drugs and their metabolites are needed. Th...

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Bibliographic Details
Main Authors: Morten Karlsen, Huiling Liu, Jon Eigill Johansen, Bård Helge Hoff
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/9/13526