Synergisms of genome and metabolism stabilizing antitumor therapy (GMSAT) in human breast and colon cancer cell lines: a novel approach to screen for synergism

Synergisms of genome and metabolism stabilizing antitumor therapy (GMSAT) in human breast and colon cancer cell lines: a novel approach to screen for synergism

Abstract Background Despite an improvement of prognosis in breast and colon cancer, the outcome of the metastatic disease is still severe. Microevolution of cancer cells often leads to drug resistance and tumor-recurrence. To target the driving forces of the tumor microevolution, we focused on syner...

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Bibliographic Details
Main Authors: Jérôme Ruhnau, Jonas Parczyk, Kerstin Danker, Britta Eickholt, Andreas Klein
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Cancer
Subjects:
Synergism
drug combination
cancer therapy
Nutlin-3
PX-478
Dichloroacetate
Online Access:http://link.springer.com/article/10.1186/s12885-020-07062-2

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http://link.springer.com/article/10.1186/s12885-020-07062-2

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