Enterocyte proliferation and signaling are constitutively altered in celiac disease.

Celiac disease (CD) occurs frequently, and is caused by ingestion of prolamins from cereals in subjects with a genetic predisposition. The small intestinal damage depends on an intestinal stress/innate immune response to certain gliadin peptides (e.g., A-gliadin P31-43) in association with an adapti...

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Bibliographic Details
Main Authors: Merlin Nanayakkara, Giuliana Lania, Mariantonia Maglio, Roberta Kosova, Marco Sarno, Alessandra Gaito, Valentina Discepolo, Riccardo Troncone, Salvatore Auricchio, Renata Auricchio, Maria Vittoria Barone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3799793?pdf=render