Thirty biologically interpretable clusters of transcription factors distinguish cancer type

Thirty biologically interpretable clusters of transcription factors distinguish cancer type

Abstract Background Transcription factors are essential regulators of gene expression and play critical roles in development, differentiation, and in many cancers. To carry out their regulatory programs, they must cooperate in networks and bind simultaneously to sites in promoter or enhancer regions...

Full description

Bibliographic Details
Main Authors: Zachary B. Abrams, Mark Zucker, Min Wang, Amir Asiaee Taheri, Lynne V. Abruzzo, Kevin R. Coombes
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Genomics
Subjects:
TCGA
Pan-cancer
Clustering
Thresher
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12864-018-5093-z

Internet

http://link.springer.com/article/10.1186/s12864-018-5093-z

Similar Items