The CCR5Δ32 Polymorphism in Brazilian Patients with Sickle Cell Disease
Background. Previous studies on the role of inflammation in the pathophysiology of sickle cell disease (SCD) suggested that the CCR5Δ32 allele, which is responsible for the production of truncated C-C chemokine receptor type 5 (CCR5), could confer a selective advantage on patients with SCD because i...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | Disease Markers |
Online Access: | http://dx.doi.org/10.1155/2014/678246 |