Antiviral Adaptor MAVS Promotes Murine Lupus With a B Cell Autonomous Role

Antiviral Adaptor MAVS Promotes Murine Lupus With a B Cell Autonomous Role

Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by increased production of autoantibodies, which commonly target nuclear antigens, and concomitant deposition of immune complexes that cause inflammation in tissues. SLE is often associated with increased systemic expression...

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Bibliographic Details
Main Authors: Wenxiang Sun, Hongsheng Wang, Chen-Feng Qi, Juan Wu, Bethany Scott, Silvia Bolland
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
MAVS
FcγRIIB
lupus
antinuclear autoantibody
germinal center
STING
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02452/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02452/full

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