Defining the temporal evolution of gut dysbiosis and inflammatory responses leading to hepatocellular carcinoma in Mdr2 −/− mouse model

Defining the temporal evolution of gut dysbiosis and inflammatory responses leading to hepatocellular carcinoma in Mdr2 −/− mouse model

Abstract Background Emerging evidence implicates the gut microbiome in liver inflammation and hepatocellular carcinoma (HCC) development. We aimed to characterize the temporal evolution of gut dysbiosis, in relation to the phenotype of systemic and hepatic inflammatory responses leading to HCC devel...

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Bibliographic Details
Main Authors: J. Behary, A. E. Raposo, N. M. L. Amorim, H. Zheng, L. Gong, E. McGovern, J. Chen, K. Liu, J. Beretov, C. Theocharous, M. T. Jackson, J. Seet-Lee, G. W. McCaughan, E. M. El-Omar, A. Zekry
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Microbiology
Subjects:
Hepatocellular carcinoma
Microbiome
Microbiota
Dysbiosis
Mdr2
Inflammatory response
Online Access:https://doi.org/10.1186/s12866-021-02171-9

Internet

https://doi.org/10.1186/s12866-021-02171-9

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