CSF Neurofilament Light Chain Levels in Primary Progressive MS: Signs of Axonal Neurodegeneration

CSF Neurofilament Light Chain Levels in Primary Progressive MS: Signs of Axonal Neurodegeneration

Objectives: Elevated neurofilament light chain (NFL) levels within the cerebrospinal fluid (CSF) are a biomarker representing axonal neurodegeneration in rapid progressive neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). It is unclear to what extent the levels of NFL increase...

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Bibliographic Details
Main Authors: Marc Pawlitzki, Stefanie Schreiber, Daniel Bittner, Julia Kreipe, Frank Leypoldt, Klemens Rupprecht, Roxana O. Carare, Sven G. Meuth, Stefan Vielhaber, Peter Körtvélyessy
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neurology
Subjects:
multiple sclerois and neuroimmunology
neurofilament light chain (NFL)
amyotrofic lateral sclerosis
primary progressive multiple sclerosis
cerebrospical fluid (CSF)
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.01037/full

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https://www.frontiersin.org/article/10.3389/fneur.2018.01037/full

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