Effects of hMASP-2 on the formation of BCG infection-induced granuloma in the lungs of BALB/c mice

Abstract Tuberculosis, caused by Mycobacterium tuberculosis, affects the functions of the lung and causes high morbidity and mortality rates worldwide. MASP-2 is an executioner enzyme, which plays an essential role in the activation of lectin pathway. In our previous studies, the MASP-2 played a dua...

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Bibliographic Details
Main Authors: Xiaoying Xu, Xiaoling Lu, Xingfang Dong, Yanping Luo, Qian Wang, Xun Liu, Jie Fu, Yuan Zhang, Bingdong Zhu, Xingming Ma
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02374-z