Mechanoregulation of YAP and TAZ in Cellular Homeostasis and Disease Progression

Biophysical cues, such as mechanical properties, play a critical role in tissue growth and homeostasis. During organ development and tissue injury repair, compressive and tensional forces generated by cell-extracellular matrix or cell-cell interaction are key factors for cell fate determination. In...

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Bibliographic Details
Main Authors: Xiaomin Cai, Kuei-Chun Wang, Zhipeng Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
YAP
TAZ
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.673599/full