Sequence-specific capture of protein-DNA complexes for mass spectrometric protein identification.

The regulation of gene transcription is fundamental to the existence of complex multicellular organisms such as humans. Although it is widely recognized that much of gene regulation is controlled by gene-specific protein-DNA interactions, there presently exists little in the way of tools to identify...

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Bibliographic Details
Main Authors: Cheng-Hsien Wu, Siyuan Chen, Michael R Shortreed, Gloria M Kreitinger, Yuan Yuan, Brian L Frey, Yi Zhang, Shama Mirza, Lisa A Cirillo, Michael Olivier, Lloyd M Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3197616?pdf=render