Investigation of radiosensitivity gene signatures in cancer cell lines.

Intrinsic radiosensitivity is an important factor underlying radiotherapy response, but there is no method for its routine assessment in human tumours. Gene signatures are currently being derived and some were previously generated by expression profiling the NCI-60 cell line panel. It was hypothesis...

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Bibliographic Details
Main Authors: John S Hall, Rohan Iype, Joana Senra, Janet Taylor, Lucile Armenoult, Kenneth Oguejiofor, Yaoyong Li, Ian Stratford, Peter L Stern, Mark J O'Connor, Crispin J Miller, Catharine M L West
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3899227?pdf=render