Rational Design, Synthesis and Preliminary Evaluation of Novel Fusarinine C-Based Chelators for Radiolabeling with Zirconium-89

Rational Design, Synthesis and Preliminary Evaluation of Novel Fusarinine C-Based Chelators for Radiolabeling with Zirconium-89

Fusarinine C (FSC) has recently been shown to be a promising and novel chelator for 89Zr. Here, FSC has been further derivatized to optimize the complexation properties of FSC-based chelators for 89Zr-labeling by introducing additional carboxylic groups. These were expected to improve the stability...

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Bibliographic Details
Main Authors: Chuangyan Zhai, Shanzhen He, Yunjie Ye, Christine Rangger, Piriya Kaeopookum, Dominik Summer, Hubertus Haas, Leopold Kremser, Herbert Lindner, Julie Foster, Jane Sosabowski, Clemens Decristoforo
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Biomolecules
Subjects:
fusarinine C (FSC)
zirconium-89
bifunctional chelator
immuno-positron emission tomography (PET)
Online Access:http://www.mdpi.com/2218-273X/9/3/91

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http://www.mdpi.com/2218-273X/9/3/91

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