Transient receptor potential melastatin 2–mediated heme oxygenase-1 has a role for bacterial clearance by regulating autophagy in peritoneal macrophages during polymicrobial sepsis
Our previous study indicated an important protective role of transient receptor potential melastatin 2 (TRPM2) in controlling bacterial clearance in macrophages during polymicrobial sepsis by regulating heme oxygenase-1. Autophagy is necessary for macrophages to kill invasive bacteria. In the presen...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2019-11-01
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Series: | Innate Immunity |
Online Access: | https://doi.org/10.1177/1753425919875796 |