A novel animal model for neuroinflammation and white matter degeneration

Small interference RNA has been widely used to suppress gene expression. Three different short hairpin RNAs (shRNAs) against dopamine D1 receptor (Drd1), driven by mouse U6 promoter in self-complementary AAV8 vector (scAAV8), were used to silence mouse striatal Drd1 expression. Transduction of mouse...

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Bibliographic Details
Main Authors: Baohu Ji, Kerin Higa, Virawudh Soontornniyomkij, Atsushi Miyanohara, Xianjin Zhou
Format: Article
Language:English
Published: PeerJ Inc. 2017-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3905.pdf