Role of hormonal and inflammatory alterations in obesity-related reproductive dysfunction at the level of the hypothalamic-pituitary-ovarian axis

Role of hormonal and inflammatory alterations in obesity-related reproductive dysfunction at the level of the hypothalamic-pituitary-ovarian axis

Abstract Background Besides being a risk factor for multiple metabolic disorders, obesity could affect female reproduction. While increased adiposity is associated with hormonal changes that could disrupt the function of the hypothalamus and the pituitary, compelling data suggest that obesity-relate...

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Bibliographic Details
Main Authors: Michelle Goldsammler, Zaher Merhi, Erkan Buyuk
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Reproductive Biology and Endocrinology
Subjects:
Obesity
Ovary
HPO
Advanced glycation end products
Monocyte chemotactic protein-1
Online Access:http://link.springer.com/article/10.1186/s12958-018-0366-6

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http://link.springer.com/article/10.1186/s12958-018-0366-6

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