Rapid Improvement of the Performance Status and Reduction of the Tumor Size in KRAS-Mutated Colorectal Cancer Patient Receiving Binimetinib, Hydroxychloroquine, and Bevacizumab

Activating RAS mutations occur in more than a half of colorectal cancers (CRCs). RAS-mutated CRCs are notoriously difficult to treat given that they are characterized by the aggressive disease course and the lack of appropriate targeted therapies. Recent preclinical studies demonstrated that RAS-mut...

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Bibliographic Details
Main Authors: Sergey V. Orlov, Magaripa A. Urtenova, Maria A. Sviridenko, Denis V. Nesterov, Tatiana N. Sokolova, Evgeny N. Imyanitov
Format: Article
Language:English
Published: Karger Publishers 2020-08-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://www.karger.com/Article/FullText/509241