Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma.

Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma.

In hematopoietic cells, serglycin proteoglycans mainly contribute to proper storage and secretion of inflammatory mediators via their negatively charged glycosaminoglycans. Serglycin proteoglycans are also expressed in cancer cells where increased expression has been linked to poor prognosis. Howeve...

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Bibliographic Details
Main Authors: Ananya Roy, Julia Femel, Elisabeth J M Huijbers, Dorothe Spillmann, Erik Larsson, Maria Ringvall, Anna-Karin Olsson, Magnus Åbrink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4880347?pdf=render

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http://europepmc.org/articles/PMC4880347?pdf=render

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