Protein Kinase D2 drives chylomicron‐mediated lipid transport in the intestine and promotes obesity

Protein Kinase D2 drives chylomicron‐mediated lipid transport in the intestine and promotes obesity

Abstract Lipids are the most energy‐dense components of the diet, and their overconsumption promotes obesity and diabetes. Dietary fat content has been linked to the lipid processing activity by the intestine and its overall capacity to absorb triglycerides (TG). However, the signaling cascades driv...

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Bibliographic Details
Main Authors: Jonathan Trujillo‐Viera, Rabih El‐Merahbi, Vanessa Schmidt, Till Karwen, Angel Loza‐Valdes, Akim Strohmeyer, Saskia Reuter, Minhee Noh, Magdalena Wit, Izabela Hawro, Sabine Mocek, Christina Fey, Alexander E Mayer, Mona C Löffler, Ilka Wilhelmi, Marco Metzger, Eri Ishikawa, Sho Yamasaki, Monika Rau, Andreas Geier, Mohammed Hankir, Florian Seyfried, Martin Klingenspor, Grzegorz Sumara
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:EMBO Molecular Medicine
Subjects:
chylomicron
fat absorption
intestine
obesity
protein kinase D2/PKD2/PRKD2
Online Access:https://doi.org/10.15252/emmm.202013548

Internet

https://doi.org/10.15252/emmm.202013548

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