Enhanced Triacylglycerol Production With Genetically Modified Trichosporon oleaginosus

Mitochondrial pyruvate dehydrogenase (PDH) is important in the production of lipids in oleaginous yeast, but other yeast may bypass the mitochondria (PDH bypass), converting pyruvate in the cytosol to acetaldehyde, then acetate and acetyl CoA which is further converted to lipids. Using a metabolic m...

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Bibliographic Details
Main Authors: Kari Koivuranta, Sandra Castillo, Paula Jouhten, Laura Ruohonen, Merja Penttilä, Marilyn G. Wiebe
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01337/full