Bioluminescent orthotopic mouse models of human localized non-small cell lung cancer: feasibility and identification of circulating tumour cells.

Bioluminescent orthotopic mouse models of human localized non-small cell lung cancer: feasibility and identification of circulating tumour cells.

BACKGROUND: Preclinical models of non-small cell lung cancer (NSCLC) require better clinical relevance to study disease mechanisms and innovative therapeutics. We sought to compare and refine bioluminescent orthotopic mouse models of human localized NSCLC. METHODS: Athymic nude mice underwent subcut...

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Bibliographic Details
Main Authors: Pierre Mordant, Yohann Loriot, Benoit Lahon, Yves Castier, Guy Lesèche, Jean-Charles Soria, Marie-Catherine Vozenin, Charles Decraene, Eric Deutsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3191172?pdf=render

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http://europepmc.org/articles/PMC3191172?pdf=render

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