Passive immunization with hypochlorite-oxLDL specific antibodies reduces plaque volume in LDL receptor-deficient mice.

AIMS: New strategies to overcome complications of cardiovascular diseases are needed. Since it has been demonstrated that atherosclerosis is an inflammatory disease, modulation of the immune system may be a promising approach. Previously, it was suggested that antibodies may confer protective effect...

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Bibliographic Details
Main Authors: Marcella van Leeuwen, Michael J Kemna, Menno P J de Winther, Louis Boon, Adriaan M Duijvestijn, Darius Henatsch, Nico A Bos, Marion J J Gijbels, Jan Willem Cohen Tervaert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3713002?pdf=render