The Ameliorative Effects of Isorhynchophylline on Morphine Dependence Are Mediated Through the Microbiota-Gut-Brain Axis

Morphine abuse is a global public health problem. Increasing evidence has shown that gut microbiota dysbiosis plays an important role in several central nervous system diseases. However, whether there is an association between gut microbiota and morphine dependence remains unclear. In this study, th...

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Bibliographic Details
Main Authors: Zhu Chen, Chen Zhijie, Zhou Yuting, Li Chan, Xiao Shilin, Zhou Qichun, Ou Jinying, Li Jing, Luo Chaohua, Mo Zhixian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.526923/full