Protective Effects of Hydrogen Sulfide Against the ATP-Induced Meningeal Nociception

Protective Effects of Hydrogen Sulfide Against the ATP-Induced Meningeal Nociception

We previously showed that extracellular ATP and hydrogen sulfide (H2S), a recently discovered gasotransmitter, are both triggering the nociceptive firing in trigeminal nociceptors implicated in migraine pain. ATP contributes to meningeal nociception by activating the P2X3 subunit-containing receptor...

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Bibliographic Details
Main Authors: Kseniia Koroleva, Elizaveta Ermakova, Alsu Mustafina, Raisa Giniatullina, Rashid Giniatullin, Guzel Sitdikova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
migraine
trigeminal nerve
mast cells
ATP
H2S
P2X3 receptor
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00266/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00266/full

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