Defining a murine ovarian cancer model for the evaluation of conditionally-replicative adenovirus (CRAd) virotherapy agents

Defining a murine ovarian cancer model for the evaluation of conditionally-replicative adenovirus (CRAd) virotherapy agents

Abstract Background Virotherapy represents a promising approach for ovarian cancer. In this regard, conditionally replicative adenovirus (CRAd) has been translated to the context of human clinical trials. Advanced design of CRAds has sought to exploit their capacity to induce anti-tumor immunization...

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Bibliographic Details
Main Authors: Rebeca González-Pastor, Ahmad Mohammad Ashshi, Adel Galal El-Shemi, Igor P. Dmitriev, Elena A. Kashentseva, Zhi Hong Lu, S. Peter Goedegebuure, Osvaldo L. Podhajcer, David T. Curiel
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Ovarian Research
Subjects:
Adenovirus
Virotherapy
Ovarian cancer
CRAd
ID8
Anti-tumor immunization
Online Access:http://link.springer.com/article/10.1186/s13048-019-0493-5

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http://link.springer.com/article/10.1186/s13048-019-0493-5

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