Immunization with a murine cytomegalovirus based vector encoding retrovirus envelope confers strong protection from Friend retrovirus challenge infection.

Immunization vectors based on cytomegalovirus (CMV) have attracted a lot of interest in recent years because of their high efficacy in the simian immunodeficiency virus (SIV) macaque model, which has been attributed to their ability to induce strong, unusually broad, and unconventionally restricted...

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Main Authors: Nadine Bongard, Vu Thuy Khanh Le-Trilling, Anna Malyshkina, Meike Rückborn, Kerstin Wohlgemuth, Ina Wensing, Sonja Windmann, Ulf Dittmer, Mirko Trilling, Wibke Bayer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008043